Plain-English translation of NCT01785420 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether , a targeted antibody treatment, can help prevent breast cancer from returning when given shortly before surgery. The study will compare women who receive this medication with women who receive a placebo (inactive saline infusion) to see if the treatment helps improve long-term outcomes and stops cancer cells from spreading.
Doctors know that cancer cells can escape into the bloodstream during surgery. This trial tests whether giving this medication in the two weeks before surgery creates an environment that makes it harder for those cells to survive and grow.
If you join this study, you will receive either a single infusion of or a placebo saline infusion over 90 minutes, given sometime in the 14 days before your scheduled surgery. Researchers will monitor you for safety and track your cancer status over time. Some participants may also have blood samples taken at specific time points to measure circulating tumor cells.
AI-generated summary from trial data · Sep 4, 2026 · Not medical advice
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