Plain-English translation of NCT01788410 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a procedure called cryoablation—which uses freezing to disable pain-transmitting nerves—guided by advanced MRI imaging in a specialized operating room. The goal is to help people with chronic pain from nerve damage or degenerative joint disease in the head, neck, or spine find lasting relief without major surgery. Researchers believe this approach may work better and last longer than current nerve-blocking treatments.
Many patients with chronic nerve pain or facet joint disease have limited options: current treatments like alcohol or numbing injections don't always work well or may carry risks. This trial exists to test whether the new treatment could provide better, longer-lasting pain relief and be safer because MRI imaging lets doctors see exactly what they're treating in real time.
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You would come to Brigham and Women's Hospital for a minimally invasive procedure in a special MRI-equipped operating room, where doctors will use freezing technology to target the painful nerves under live MRI guidance. You'll need to complete imaging scans before and after the procedure and attend follow-up visits to track your pain relief over time. The entire process is designed to be less invasive than traditional surgery, with the goal of reducing your pain for months.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Brigham and Women's Hospital
Enrollment target
~50 participants
Started
May 2013
Primary completion
May 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2023.
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Central contact
Thomas Lee, MD
Brigham and Women's Hospital
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