Plain-English translation of NCT01790152 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is following young cancer survivors to understand how dexrazoxane — a medication given during cancer treatment — may protect the heart from damage. Researchers will compare heart health markers (special blood tests and heart imaging) in survivors who received dexrazoxane during their cancer therapy with those who did not. The goal is to learn whether this medication truly prevents serious heart problems that can develop years after cancer treatment ends.
Some childhood cancers are treated with chemotherapy drugs and chest radiation that can damage the heart and lead to heart failure later in life. This medication was designed to prevent that damage, but researchers need to confirm it actually works and understand which patients benefit most from it.
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You will visit a research center for a single appointment where you'll complete a symptom checklist, have a physical exam, undergo a heart ultrasound (echocardiogram), walk for 6 minutes to test your fitness, and provide a blood sample for heart health markers. You'll also answer brief questionnaires about your quality of life, family history, physical activity, and smoking. The entire visit typically takes a few hours. Researchers may also review your existing medical records from your cancer treatment to gather important information about your care.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States