Plain-English translation of NCT01852448 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Cystic Fibrosis research guide →Researchers want to understand why some people with cystic fibrosis develop problems with insulin and blood sugar control, while others don't. By looking at genetic differences and studying how the body produces insulin, they hope to identify which people are at higher risk. This knowledge could lead to better prevention and treatment strategies in the future.
Cystic fibrosis-related diabetes can make lung and nutritional problems worse and reduce how long people live. Doctors have always assumed it was simply caused by pancreatic damage, but recent discoveries suggest genetics also plays a major role — similar to how genes affect type 2 diabetes in the general population.
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You will give one blood or saliva sample and allow the research team to review your medical records. That's it — there are no repeat visits or ongoing treatments involved. The researchers will check your sample for genetic variations and compare your results with others in the study to look for patterns.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Children's Hospital of Philadelphia
Collaborators
University of Pennsylvania
Enrollment target
~550 participants
Started
May 2013
Primary completion
July 2026
Age range
2 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachel Walega
Children's Hospital of Philadelphia
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.