Plain-English translation of NCT01882205 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
People with longstanding ulcerative colitis have a higher risk of developing colon cancer, so they need regular screening colonoscopies. This study compares several advanced camera techniques—some using a special blue dye called methylene blue, and others using special computer filters—to see which method best detects early warning signs of cancer during a colonoscopy exam.
Current guidelines for screening colonoscopies in ulcerative colitis patients require taking many random tissue samples, but research suggests that using special imaging techniques to target suspicious areas could find more cancer warning signs while taking fewer samples. This study will determine which imaging method works best.
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You will come in for a colonoscopy screening appointment. Depending on which study group you're randomly assigned to, your doctor will use one of three different camera imaging systems (from different manufacturers) combined with either the special blue dye or special computer filters to examine your colon. The doctor will take biopsies (small tissue samples) of any suspicious areas found during the exam, and these will be checked for early cancer warning signs. The entire procedure is similar to a standard colonoscopy.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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