Donate tissue samples to help understand kidney dialysis complications

Recruiting

What is this trial?

This is a research study that collects small tissue samples (called biopsies) from the lining of the abdomen in patients with advanced kidney disease, particularly those undergoing peritoneal dialysis — a type of kidney treatment. Researchers are building a library of these tissue samples to study how dialysis affects the body and to find ways to improve treatment outcomes for both children and adults with kidney failure.

Peritoneal dialysis is a life-saving treatment for people whose kidneys no longer work, but doctors don't fully understand how the treatment affects the body's tissues over time. By collecting and studying these samples, researchers hope to improve dialysis techniques, prevent complications, and develop better treatments for kidney disease.

Do you qualify?

You likely qualify if…

you are between newborn and 90 years old
you have been diagnosed with advanced chronic kidney disease (stage 5) or are currently on peritoneal dialysis
you are scheduled for abdominal surgery for non-kidney reasons (such as hernia repair or gallstone removal)
you have received a kidney transplant after dialysis
you or your parent/guardian are able to give written informed consent

You likely don't qualify if…

you have significant abdominal scarring, birth defects, or abdominal inflammation beyond what dialysis typically causes
you have advanced cancer that has spread throughout your body
you have severe heart failure or other serious medical conditions where a biopsy procedure could be unsafe
you are pregnant
you were born before 37 weeks of pregnancy or have very low blood hemoglobin levels

What participation looks like

If you qualify, a small tissue sample would be collected from your peritoneum (the lining of your abdomen) during a procedure you are already having — such as when your dialysis catheter is placed, during dialysis treatment, or during abdominal surgery. The sample collection adds minimal time and risk to a procedure you would be having anyway. There are no ongoing visits or follow-up appointments required beyond normal dialysis or transplant care.

Building a tissue bank from kidney dialysis patients

What is this trial?

Do you qualify?

What participation looks like

Trial locations(26 sites)