Plain-English translation of NCT01928732 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial examined two types of talk therapy for treating PTSD in veterans: Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT). Both treatments had been shown to help people with PTSD, but doctors didn't have clear evidence about which one worked better. The study enrolled over 900 male and female veterans to compare these two approaches side by side.
PTSD affected a large and growing number of veterans, and while both of these therapies showed promise, doctors needed definitive evidence about how they compared to each other. This was the first large-scale study designed to answer that question.
Participants received weekly therapy sessions for approximately 12 weeks, with flexibility to finish in 10–11 sessions if improving quickly or extend to 14 sessions if more time was needed. Participants were randomly assigned to receive either Prolonged Exposure or Cognitive Processing Therapy. They completed assessments before, during, and after treatment to measure how much their PTSD symptoms improved, and some interviews were conducted by phone.
AI-generated summary from trial data · Aug 18, 2026 · Not medical advice
United States