Imaging scan to find problem areas in the pancreas

This trial tests Fluorodopa F 18, a specialized imaging scan combined with a CT scan, to help doctors find exactly where problems are occurring in the pancreas of children with congenital hyperinsulinism or insulinoma. The scan uses a radioactive tracer that lights up pancreatic cells, making it easier for surgeons to plan surgery precisely. This approach has already been used safely in over 200 patients worldwide and is considered the best way to prepare for pancreatic surgery in children who need it.

Children with congenital hyperinsulinism produce too much insulin, which causes dangerously low blood sugar that can harm the brain. When medicines don't work, surgery is the only option—but doctors need to know exactly where the problem is in the pancreas. Current methods to find these problem areas are invasive and risky; this medication offers a safer, more accurate way to guide surgeons.