Plain-English translation of NCT02043457 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This trial is designed to help doctors understand what makes some people successful at losing weight and maintaining that loss long-term. Researchers recognize that weight management isn't one-size-fits-all, so they're studying how your body, biology, and behaviors affect your weight loss success. By learning more about these individual differences, they hope to create personalized weight management strategies that work better for each person.
Most weight loss programs treat everyone the same way, but this doesn't work well for everyone. This study exists to figure out what personal factors—like your metabolism, genetics, eating behaviors, and mental health—predict who will succeed with weight loss and keep the weight off long-term.
You likely qualify if…
You likely don't qualify if…
You would join the Weight Management Program at the University of Michigan, where you'll work on losing weight through lifestyle changes. Throughout the study, researchers will perform various measurements to understand how your body responds—including blood tests, muscle and fat tissue samples, fitness testing, and surveys about your mood and eating behaviors. These detailed measurements happen at the start, after you've lost 10-15% of your weight, and again after 2 years of maintaining your weight loss.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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