Plain-English translation of NCT02172651 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether supplementation taken for 2–4 weeks before surgery can help fight colon cancer. Researchers want to understand how vitamin D interacts with cancer cells and whether higher doses might be more beneficial than standard doses. You would take either a high dose or standard dose of (or a placebo) daily before your scheduled surgery.
Laboratory research suggests that vitamin D may play a role in slowing cancer growth, but doctors don't yet know whether giving patients this medication before surgery is truly helpful or what dose works best. This study aims to gather evidence about how the medication works in people with colon cancer.
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You would take one capsule by mouth once daily for 14–28 days leading up to your scheduled colon cancer surgery. The capsule would contain either a high dose of vitamin D, a standard dose, or a placebo—you won't know which. Before surgery, researchers will collect blood samples and, during surgery, they will collect tissue samples to study how vitamin D affects your cancer cells. You'll keep a simple diary to track when you take the medication.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
United States