Plain-English translation of NCT02253251 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers have discovered that certain genetic mutations — specifically in how microRNA (a type of genetic regulator) binds to genes like KRAS — may predict who is at higher risk for cancer, endometriosis, and fertility problems. This study asks you to provide a saliva sample and answer questions about your lifestyle and health history so scientists can better understand how these mutations work and how they affect cancer risk and how people respond to cancer treatment.
Doctors and researchers need to understand which people are at highest risk for cancer because of their genes, and which cancer treatments work best for people with these specific genetic changes. This information could help prevent cancer and improve treatment outcomes for future patients.
You likely qualify if…
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You will provide a saliva sample for genetic testing and complete questionnaires about your lifestyle, health history, and family medical background. The researchers may ask for permission to store your genetic information for future research into similar mutations. Depending on which group you join, you may be followed over time and asked to answer additional health surveys to help scientists understand how lifestyle factors affect cancer risk in people with these genetic mutations.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Sponsor
MiraKind
Enrollment target
~15,000 participants
Started
September 2014
Primary completion
December 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Joanne Weidhaas, MDPhD
MiraKind
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.