Plain-English translation of NCT02290795 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how the vitreous—the gel-like substance that fills the back of your eye—may affect your optic nerve and influence how glaucoma develops or progresses. As you age, this gel naturally changes and can pull on different parts of the retina and optic nerve. This study will compare how the gel's attachment affects healthy eyes, eyes with glaucoma, and eyes being treated with ocriplasmin (a medication that dissolves certain attachments in the eye).
Current glaucoma tests focus on the optic nerve itself, but doctors may not fully understand how the eye's gel layer affects those test results or even contributes to glaucoma itself. By studying this relationship in different groups of people, researchers hope to improve how they diagnose and monitor glaucoma.
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You will visit the research center for detailed eye imaging and scanning tests that allow doctors to see the structure of your optic nerve and the gel layer inside your eye. The study compares results across four groups: healthy volunteers, glaucoma patients, glaucoma patients preparing for surgery, and patients scheduled to receive ocriplasmin treatment. Your participation involves completing these specialized eye scans; no medication or invasive procedures are part of the study itself.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
Belgium
Sponsor
Universitaire Ziekenhuizen KU Leuven
Enrollment target
~350 participants
Started
November 2014
Primary completion
April 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ingeborg Stalmans, MD, PhD
Dpt. Ophthalmology, University Hospitals Leuven, Belgium
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.