Plain-English translation of NCT02379429 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Bladder Cancer research guide →This is a research study run by the National Cancer Institute that collects tissue, blood, urine, and saliva samples from people with bladder cancer (also called urothelial cancer) and from healthy volunteers. The goal is to study the genetic and molecular changes that cause bladder cancer, so that researchers can develop new, targeted treatments that work better than what's currently available.
Bladder cancer hasn't had major new treatment advances in over 20 years, and it's very expensive to treat. By studying the genetic blueprint of bladder cancer cells and comparing them to healthy tissue, researchers hope to identify new targets for therapy—similar to how genetic research on kidney cancer led to several FDA-approved drugs.
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If you have bladder cancer, you will donate tissue samples (usually collected during procedures you're already having for diagnosis or treatment), along with blood and urine samples. If you're a healthy volunteer, you'll provide blood, saliva, and urine samples once. The study is ongoing and aims to enroll 500 people total—both patients and healthy volunteers—to build a large collection of samples that researchers can use to understand how bladder cancer develops and test new ideas for treatment.
AI-generated summary from trial data · Aug 19, 2026 · Not medical advice
United States