Plain-English translation of NCT02381990 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term study tracking men who receive cryotherapy — a freezing treatment for early prostate cancer — using advanced imaging (MRI and ultrasound) to precisely target the cancer. The study is enrolling up to 5,000 men to collect detailed information about how well this treatment controls cancer and how it affects urinary and sexual function over many years.
Cryotherapy is a less invasive alternative to surgery or radiation for some men with early prostate cancer, but doctors need long-term data to understand how well it works and how it impacts men's quality of life compared to other treatment options.
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After your cryotherapy procedure, you would provide detailed health information and undergo regular follow-up appointments over 5 to 15 years. Visits include PSA blood tests, imaging scans (MRI yearly for the first few years), biopsies to check the treated area, and questionnaires about urinary function, sexual function, and quality of life. You'll also have the option to use a smartphone app to monitor your health between appointments.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States
Sponsor
Urological Research Network, LLC
Enrollment target
~5,000 participants
Started
August 2013
Primary completion
August 2023
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
55 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in January 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
CIELO D GUERRA, BS
UROLOGICAL RESEARCH NETWORK
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.