Plain-English translation of NCT02422238 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term research study that follows people with non-alcoholic fatty liver disease (a condition where fat builds up in the liver without alcohol being the cause) to understand why some people's disease gets worse over time and others stay stable. Researchers will collect blood, urine, stool, and breath samples, along with imaging scans, to identify early warning signs and develop better treatments.
Fatty liver disease affects millions of people but often progresses silently without symptoms. This study aims to identify which patients are at highest risk for serious complications like cirrhosis or liver cancer, so doctors can intervene earlier and prevent life-threatening outcomes.
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You will visit the clinic to complete questionnaires about your health and lifestyle, have your body measurements taken, and undergo imaging scans (MRI and bone density scans). You'll also donate blood, urine, stool, and breath samples for laboratory analysis. After 5 and 10 years, you'll return for the same tests and sample collection to allow researchers to track how your liver health changes over time.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Netherlands
Sponsor
Maastricht University Medical Center
Collaborators
Centrum Obesitas-Eetstoornissen (CO-EUR)
Enrollment target
~500 participants
Started
June 2015
Primary completion
December 2017
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in September 2016.
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