Plain-English translation of NCT02423395 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
Muscle cramps are a common and painful problem for people with liver cirrhosis, and current treatments don't work well for everyone. This study is testing whether a medication called can safely and effectively reduce these cramps. Half of the participants will receive the medication, and half will receive a placebo (a pill with no active medicine) to see if the treatment really works.
Doctors know that muscle cramps significantly hurt people's quality of life when they have liver disease, but there is no clear best treatment yet. This study aims to find out whether this medication can help where other treatments have fallen short.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive either the medication or a placebo, and you'll take your assigned pill twice daily for one month. During this time, you'll likely have follow-up visits or check-ins to report how often you're having cramps and how well the treatment is working. Your role is simply to take the pill as directed and honestly report your symptoms.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Egypt
Large-scale testing
Sponsor
Sherief Abd-Elsalam
Collaborators
Tanta University
Enrollment target
~100 participants
Started
January 2015
Primary completion
December 2028
Last updated on clinicaltrials.gov in June 2019.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sherief M Abd-Elsalam, lecturer
TUH
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.