A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression

Completed

Plain-English translation of NCT02493868 on ClinicalTrials.gov ↗ · Source last updated April 2025 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(155 sites)

United States

Birmingham, Alabama

Little Rock, Arkansas

Anaheim, California

Garden Grove, California

Glendale, California