Plain-English translation of NCT02578810 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at whether three new tools—a brain activity measurement called BIS, two specific blood tests, and a risk prediction model called PIERS—can help doctors better identify and predict severe pregnancy-related high blood pressure (called eclampsia and preeclampsia). Researchers will compare these measurements in pregnant women who have developed severe high blood pressure with healthy pregnant women to see if the tools can accurately detect who is at highest risk.
Severe high blood pressure during pregnancy is a leading cause of serious illness and death for mothers worldwide. Right now, doctors don't have perfect tools to predict which women will develop the most dangerous form of this condition. This study aims to find better, faster ways to identify at-risk patients so they can receive closer monitoring and earlier treatment.
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If you join this study, you would have a painless 20-minute recording of your brain activity using sensors on your scalp, and blood samples would be taken to measure specific markers. Your medical information would be reviewed and entered into a risk prediction calculator. The study compares measurements from 24 pregnant women with severe high blood pressure to 24 healthy pregnant women to see if these tools can predict who will develop serious complications.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Malaysia
Sponsor
Suez Canal University
Collaborators
University of Malaya
Enrollment target
~48 participants
Started
October 2016
Primary completion
December 2030
Age range
18 Years – 50 Years
Sex
Female only
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Ashraf Dahaba, MD
Guest Professor
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