Plain-English translation of NCT02590822 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether two different lifestyle approaches—either a medically supervised, very-low-calorie meal replacement diet or a three-times-weekly supervised exercise program—can improve a specific type of heart dysfunction in people with type 2 diabetes. The trial will compare these two approaches to standard diabetes care to see which works best at reversing early heart problems that often go unnoticed.
Many people with type 2 diabetes develop subtle heart problems that don't cause obvious symptoms but can lead to serious complications later. This study wants to know whether aggressive lifestyle changes can actually reverse this hidden heart damage before it becomes dangerous.
You likely qualify if…
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If you join, you'll first have baseline heart imaging and tests, then be randomly assigned to one of three groups for 12 weeks: standard diabetes care with weekly support calls, a very-low-calorie meal replacement diet (810 calories daily) with health coaching, or supervised exercise sessions three times per week for one hour each. After 12 weeks, you'll be followed up at 6 and 12 months with repeat heart imaging and blood tests to see if your heart function has improved.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
United Kingdom