Plain-English translation of NCT02621021 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a combination treatment for melanoma that has spread throughout the body. The treatment involves collecting immune cells called lymphocytes from your tumor, growing more of them in the lab, and then putting them back into your body along with and another immune-boosting medication. Researchers want to see if adding to this cell therapy improves how well it works.
Some patients with advanced melanoma don't respond well enough to current treatments, or their cancer comes back. This trial is exploring whether combining immune cells with can help more patients achieve lasting remission.
You likely qualify if…
You likely don't qualify if…
First, doctors will surgically remove one of your tumors to collect immune cells from it. You'll then receive chemotherapy to prepare your body, followed by an infusion of your own grown immune cells plus high-dose medication to boost them. You may also receive , depending on which study group you're assigned to. You'll need multiple hospital visits for treatment and monitoring, and close follow-up care for several months after treatment ends to watch for side effects and measure how well the treatment worked.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States