Plain-English translation of NCT02647827 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a medication commonly used to improve blood sugar control, or acupuncture combined with lifestyle changes can help women with polycystic ovary syndrome (PCOS) become more sensitive to insulin. PCOS is a condition that affects how your body produces hormones and processes blood sugar. The study wants to see which approach works best to prevent or delay the development of type 2 diabetes.
Women with PCOS often have trouble with insulin resistance—meaning their bodies don't respond well to insulin, the hormone that helps control blood sugar. This can eventually lead to type 2 diabetes. Researchers want to find out whether this medication or acupuncture, alongside lifestyle management, can help prevent this serious complication.
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If enrolled, you will be randomly assigned to one of three groups: lifestyle management only, lifestyle management plus acupuncture (3 times per week for 4 weeks, then twice weekly for 12 weeks), or lifestyle management plus daily tablets. All participants will receive lifestyle guidance at the start. Over 4 months, you'll have visits to measure your blood sugar response, hormone levels, and overall health. You may also have blood tests and tissue biopsies to help researchers understand how the treatments work at a deeper level.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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