Plain-English translation of NCT02664831 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After cardiac arrest, the body goes through significant stress and inflammation. This study is trying to understand why some people recover well while others have lasting brain damage. Researchers will collect blood samples and track medical information from cardiac arrest patients to identify differences in how the immune system responds and heals.
Currently, doctors cannot predict who will have the best recovery after cardiac arrest. Early evidence suggests that differences in how each person's immune cells work — and how well their body controls inflammation — may explain why outcomes vary so much. This research aims to find these patterns so doctors can eventually develop better treatments to help people recover.
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As a participant, you would have blood samples drawn at different time points while you're in intensive care. Researchers will also review your medical records and track your recovery and neurological outcomes over time. The study does not involve taking new medications — it is purely observational, meaning doctors are watching and learning from your care, not testing a new treatment.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States
National Institute of General Medical Sciences (NIGMS), National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~400 participants
Started
January 2016
Primary completion
January 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
David B Seder, MD
MaineHealth
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.