Plain-English translation of NCT02685969 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Alzheimer's Disease research guide โThis research study uses two specialized brain imaging techniques to detect early signs of Alzheimer's disease in cognitively normal people. The first scan looks for buildup of a protein called amyloid in the brain, which is thought to be an early marker of Alzheimer's. The second scan measures how the brain is using glucose (sugar) for energy. Together, these scans help researchers understand how the disease develops before symptoms appear.
Alzheimer's disease develops slowly over many years, often without obvious symptoms at first. By studying people who still have normal thinking and memory, researchers hope to identify early warning signs and better understand how the disease progresses, which could eventually lead to earlier treatment or prevention strategies.
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You will undergo two specialized brain imaging scans on the same day or over a short period. First, you'll receive an injection of a harmless tracer (a radioactive substance that helps the imaging machine see what's happening in your brain), then you'll lie still in a PET scanner for about 20โ30 minutes while it takes pictures. You'll repeat this process with a second tracer to measure glucose use. The scans are painless, though you'll need to stay still, and the radioactive tracer leaves your body naturally within hours.
AI-generated summary from trial data ยท Jun 10, 2026 ยท Not medical advice
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