Plain-English translation of NCT02720679 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at St. Jude Children's Research Hospital want to understand why some people develop certain blood disorders by studying their genes and family history. By analyzing blood samples from you and your relatives, they hope to find the genetic mutations responsible for conditions like sickle cell disease, aplastic anemia, and other inherited blood problems. This information could help doctors better understand and treat these conditions in the future.
Many blood disorders run in families, but doctors don't always know exactly which genes cause them or how they're inherited. By studying the genes of people with these conditions and their relatives, researchers can identify the root causes and potentially develop better treatments.
You likely qualify if…
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You would provide a blood sample (and possibly a bone marrow sample if you're already scheduled for one for medical reasons). You'll also share your medical history and family background with the research team. If you're comfortable with it, researchers may contact you once a year to ask how you're doing and whether anything has changed in your health or family medical history.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States
Collaborators
Boston Children's Hospital, University of Memphis
Enrollment target
~1,716 participants
Started
June 2016
Primary completion
July 2040
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Marcin Wlodarski, MD, PhD
St. Jude Children's Research Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.