Plain-English translation of NCT02720679 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at St. Jude Children's Research Hospital want to understand why some people develop inherited blood disorders — conditions that affect how blood cells form or function. By analyzing blood samples from patients and their biological family members using advanced genetic testing, they hope to identify the specific genetic changes responsible for these diseases and learn how different genes influence who gets sick and how severely.
Many blood disorders run in families but doctors don't always know exactly which genetic change is causing them. By studying families together, researchers can pinpoint the culprit genes and eventually develop better treatments or earlier diagnoses for people with these conditions.
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You will meet with a geneticist or genetic counselor who will review your family history and explain what genetic testing means for you. You'll provide a blood sample, and if you're already having a bone marrow procedure for medical reasons, researchers may collect an extra sample then. If you agree, the research team will contact you once a year to check on your health and any changes in your family's medical history.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Collaborators
Boston Children's Hospital, University of Memphis
Enrollment target
~1,716 participants
Started
June 2016
Primary completion
July 2040
Last updated on clinicaltrials.gov in November 2025.
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Central contact
Marcin Wlodarski, MD, PhD
St. Jude Children's Research Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.