Recruiting

Bone marrow stem cells for nervous system disorders

Plain-English translation of NCT02795052 on ClinicalTrials.gov ↗ · Source last updated June 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing a treatment called bone marrow-derived stem cells (BMSC) for people with nervous system diseases or injuries. Researchers will collect stem cells from your bone marrow, then give them back to you through an IV infusion and by applying them to the inside of your nose. The hope is that these cells may help repair nerve damage and improve your symptoms.

Many nervous system conditions—like Parkinson's disease, ALS, stroke, and dementia—cause lasting damage that current medicines and surgeries can't reverse. This trial exists to see whether stem cells from your own bone marrow might repair that damage and restore some lost function.

Do you qualify?

You likely qualify if…

you have a diagnosed nerve or brain disorder that has caused lasting damage unlikely to improve with current standard treatments
your condition has been present for at least 6 months
you are 18 years or older and able to give informed consent
you are medically stable and able to get clearance from your primary care doctor to undergo the procedure
the research team believes you could benefit from stem cell treatment and that the procedure poses minimal risk to your health

You likely don't qualify if…

you are unable to cooperate with neurologic exams or follow-up appointments needed for the study
you are not medically stable or have significant health risks that would make the procedure unsafe
you are a woman of childbearing age and are pregnant, or unwilling to avoid pregnancy for 3 months after treatment
you cannot provide informed consent or understand the study requirements

What participation looks like

If you qualify, your bone marrow will be collected through a procedure, and stem cells will be separated from it. You'll then receive these cells both through an IV infusion into your bloodstream and through application to the inside of your nasal passages (lower part of the nose). After treatment, you'll need to return for follow-up neurologic exams with the research team or your own neurologist to see if your symptoms improve. The study is still recruiting participants.

AI-generated summary from trial data · Jun 7, 2026 · Not medical advice

Trial locations(3 sites)

United States

MD Stem Cells, Westport, Connecticut

MD Stem Cells, Coral Springs, Florida

United Arab Emirates

The Saudi-German Hospital, Dubai