Plain-English translation of NCT02804074 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The MASTER study is testing two different ways to manage high blood pressure that appears controlled when measured in a doctor's office, but is actually high when measured outside the office over 24 hours. Half of participants will have their treatment adjusted based on office blood pressure readings, while the other half will have treatment adjusted based on 24-hour home blood pressure monitoring. Researchers want to see which approach better protects your heart and kidneys over time.
Many people have blood pressure that looks normal in the doctor's office but is actually elevated at home — a condition called masked hypertension. Doctors don't yet know whether treating based on office readings or home readings leads to better health outcomes, so this study aims to find the answer.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of two groups: either your blood pressure medications will be adjusted based on office blood pressure readings, or based on 24-hour ambulatory monitoring that you'll wear periodically. Throughout the study, you'll visit the clinic for regular check-ups to measure your blood pressure, undergo kidney and heart assessments, and provide urine samples. The study lasts 4 years total, with the most intensive monitoring during the first year.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Italy
Venezuela