Plain-English translation of NCT02815683 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This is a long-term study following patients with severe emphysema who receive one-way endobronchial valves โ small devices placed inside the airways to reduce lung volume and improve breathing. Researchers will track how well the treatment works, whether it improves lung function and exercise capacity, and whether the benefits seen in earlier clinical trials actually happen in everyday medical practice across the Netherlands.
New bronchoscopic treatments for emphysema have shown promise in controlled trials, but doctors need to know whether these benefits hold true when patients receive the treatment at different hospitals in routine care. This study will create a national database to monitor safety, effectiveness, and outcomes โ and to help optimize how this new treatment is used going forward.
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You will receive the one-way valve treatment as planned by your doctor, and the research team will collect information about your procedure and health outcomes over 5 years. They will monitor how well your lungs are working after treatment using imaging scans (like a CT scan 30 days after the procedure) and other standard clinical assessments. Your data will be entered into a national database to help doctors understand how this treatment performs in real-world settings across the Netherlands.
AI-generated summary from trial data ยท Jun 2, 2026 ยท Not medical advice
Netherlands
Sponsor
University Medical Center Groningen
Enrollment target
~500 participants
Started
September 2016
Primary completion
January 2028
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Karin Klooster, PhD
University Medical Center Groningen
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.