Plain-English translation of NCT02864485 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a living donor liver transplant can help people with colorectal cancer that has spread to their liver but cannot be removed by standard surgery. Participants will receive chemotherapy first to make sure their cancer is stable, and then, if they have a willing healthy living donor, they will receive a liver transplant that removes all the cancer-affected tissue. The research team hopes this approach will give patients a better chance of long-term survival.
Most people with colorectal cancer that spreads to the liver cannot have surgery to remove it, which limits their treatment options and survival chances. A liver transplant would remove all the cancer at once, but it has rarely been tried for this type of cancer. This trial aims to see if using strict selection criteria and careful chemotherapy beforehand can make this treatment work safely and effectively.
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If you join this trial, you will work closely with the transplant team over several months. You will continue chemotherapy to keep your cancer stable and be monitored regularly with blood tests and scans to make sure your disease is not progressing. Once your medical team confirms you are ready and your living donor has been evaluated and approved, you will undergo liver transplant surgery to have your diseased liver removed and replaced with the donor's liver. After transplant, you will have regular follow-up visits to monitor your recovery and watch for any signs of cancer recurrence.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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