Plain-English translation of NCT02877303 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new treatment approach for adults with a type of blood cancer called B-cell acute lymphoblastic leukemia. The study combines standard chemotherapy drugs with two newer targeted medications: and . Researchers want to see if this combination helps patients stay cancer-free longer and improves survival.
B-cell acute lymphoblastic leukemia is a serious cancer that is difficult to treat, especially in adults. While standard chemotherapy helps some patients, many experience cancer recurrence. This trial exists to find out whether adding the newer targeted medications to chemotherapy can improve long-term outcomes and give patients better chances of staying in remission.
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You would receive four cycles of intensive chemotherapy (given every 3 weeks), during which you take multiple drugs by mouth and receive intravenous infusions, with some medications injected into the fluid around your spine. After completing chemotherapy, you then receive and as continuation therapy over several more cycles. Throughout treatment, you would have frequent clinic visits and blood tests to monitor how well the treatment is working and to watch for side effects. The entire treatment course takes several months.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States