Plain-English translation of NCT02878408 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers believe that a virus that lives dormant in our DNA (called a human endogenous retrovirus) may play a role in bipolar disorder and schizophrenia. This study collects blood samples from people with these conditions at different stages of illness to measure whether this virus becomes active and triggers inflammation in the body. By comparing blood samples from patients and healthy people, the researchers hope to understand whether controlling this virus could help treat these mental health conditions.
Previous studies suggest that this dormant virus may reactivate and cause inflammation in people with bipolar disorder and schizophrenia, but scientists need more evidence. This trial aims to confirm that link and understand how environmental factors and genes interact to trigger the virus, which could eventually lead to new treatments.
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If you're in the study, you'll come in for blood draws and answer questions about your health and background. People who are hospitalized for a mental health crisis will have samples taken during their hospital stay and again when they leave. People who are stable or healthy will have one visit. The whole process involves blood work and health questionnaires—no medications or invasive procedures.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France