Plain-English translation of NCT02916810 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing transcranial magnetic stimulation (TMS) — a non-invasive procedure that uses magnetic pulses to gently stimulate specific areas of the brain — as a treatment for people with schizophrenia who continue to hear voices despite taking antipsychotic medications. The key innovation is that researchers will use brain imaging to personalize the treatment location for each individual, potentially making it more effective than standard approaches.
Some research shows that this treatment can help reduce hallucinations, but results have been mixed and inconsistent in larger groups of patients. This study aims to develop a more targeted approach using brain imaging to identify the best spot for each person, which could help more patients benefit from the treatment.
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If you join this study, you'll first have an MRI brain scan so researchers can create a personalized treatment plan for you. Then you'll receive magnetic stimulation sessions targeting your specific brain areas. Half of participants will receive active treatment and half will receive a sham (placebo) version, though researchers will work to identify your individual treatment target. You'll have regular visits with the study team and will need to stay in contact with them throughout your participation, along with maintaining care with your regular mental health provider.
AI-generated summary from trial data · Aug 4, 2026 · Not medical advice
United States