Plain-English translation of NCT02945579 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether certain breast cancer patients who have an excellent response to chemotherapy can safely avoid breast surgery and instead be treated with radiation therapy alone. Researchers want to see if patients whose tumors shrink dramatically after chemotherapy can maintain good outcomes without undergoing surgery, while still having regular imaging and biopsies to monitor for any signs of cancer returning.
Surgery to remove breast tissue can affect how a woman's breast looks and feels, and some patients may experience pain or loss of function. This trial exists to see if patients whose cancers respond very well to chemotherapy might be able to skip surgery and rely on radiation therapy instead, potentially reducing side effects while maintaining safety.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will first receive standard chemotherapy (or hormone therapy, depending on your cancer type). After your chemotherapy is complete, doctors will use imaging and a small biopsy to check if your cancer has shrunk significantly. If it has, you will receive radiation therapy to your breast over several weeks instead of surgery. You will then have follow-up visits with imaging every 6 months for up to 10 years, and complete questionnaires about your comfort with the decision, your quality of life, and how your breast looks and feels.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States