Plain-English translation of NCT02969798 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Diabetes Mellitus, Type 2 research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing four different medications—, , , and —to see which one works best at preserving your pancreas's ability to control blood sugar in people with early warning signs of type 2 diabetes. Researchers will compare how well each medication helps your body handle glucose and keeps your pancreas healthy. The goal is to stop or slow the progression from pre-diabetes to full diabetes.
Pre-diabetes is an early stage where blood sugar levels are higher than normal but not yet diabetic. Right now, there's no clear best way to treat it. This trial exists to find out whether treating pre-diabetes early with medication can prevent or delay the development of type 2 diabetes by keeping your pancreas working as well as possible.
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You will visit the research center multiple times over several months for blood tests, glucose tolerance tests, and physical exams to measure how your pancreas and body are responding. You'll be randomly assigned to take one of the four medications by mouth every day at a set dose (which may increase after the first month or two). Throughout the study, researchers will monitor your blood sugar levels, insulin function, and overall health to see how well the medication is working.
AI-generated summary from trial data · Jul 22, 2026 · Not medical advice
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