Plain-English translation of NCT02972372 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat advanced esophageal squamous cell cancer in Chinese patients. You would be randomly assigned to receive either chemotherapy with 5-fluorouracil combined with radiation therapy over 5–6 weeks, or surgery to remove the affected portion of your esophagus. The study will follow you for 5 years to see which approach helps patients live longer and stay cancer-free.
Esophageal cancer is especially common in China, but doctors need better evidence about whether chemotherapy with radiation or surgery works better for patients with advanced, resectable tumors. This trial aims to answer that important question so future patients can receive the most effective treatment.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to one of two groups. If you receive chemotherapy and radiation, you will have treatment visits over 5–6 weeks where you receive chemotherapy drugs and radiation therapy. If you are assigned to surgery, you will have a surgical procedure to remove the affected part of your esophagus. Both groups will have follow-up visits and scans over 5 years to monitor your health and check for cancer recurrence.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
China
Sponsor
The First Affiliated Hospital of Henan University of Science and Technology
Collaborators
Jiangsu HengRui Medicine Co., Ltd., Anyang Tumor Hospital
Enrollment target
~196 participants
Started
November 2016
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Shegan Gao, MD, PhD
The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.