Plain-English translation of NCT02973633 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers are testing whether a special type of MRI scan called diffusion tensor imaging can detect early changes in heart muscle structure that happen before heart failure develops. The study will follow people who have recently had a heart attack or have thickened heart muscle, comparing their results to healthy volunteers. This imaging technique may help doctors understand and predict who will develop heart failure.
Heart failure often develops gradually over time as the heart's structure changes, but doctors don't yet fully understand these early changes or how to predict who will become sick. This study aims to identify those early warning signs so patients at risk can be identified and treated sooner.
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You will visit the hospital multiple times for MRI scans of your heart. Each scan takes about 30–60 minutes and involves lying still in an MRI machine while it takes detailed pictures of your heart muscle. You may be asked to hold your breath briefly during the scan. Some participants may receive a contrast dye injection (a special substance that helps the images clearer), while others will not. The researchers will compare your scans over time to track any changes in your heart muscle.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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