Plain-English translation of NCT03008291 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying a newer technique for placing pacemaker leads—the thin wires that help your heart beat properly. Instead of the traditional placement method, researchers want to test whether placing leads in a specific location called the His bundle or left bundle area can work better for people with heart failure or dangerous heart rhythms. The goal is to see if this placement helps the heart work more efficiently and improves how the electrical signals move through your heart.
Many people with heart failure don't respond well enough to standard pacemaker treatments, and some have electrical problems in their heart's conduction system that aren't being fixed properly. This trial exists to see whether this new placement technique can offer better results for these patients.
You likely qualify if…
You likely don't qualify if…
If you qualify, your doctor will already be recommending that you receive a pacemaker as part of your standard care. By joining this study, you'll undergo the pacemaker implant procedure as planned, but the research team will collect extra heart rhythm measurements during your surgery to better understand how this newer placement technique affects your heart's electrical system. You won't need extra visits or procedures beyond what your doctor has already recommended.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States
Enrollment target
~80 participants
Started
October 2016
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Yong-Mei Cha, M.D.
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.