Plain-English translation of NCT03050268 on ClinicalTrials.gov ↗ · Source last updated ·
This research study invites families affected by cancer — especially cancer diagnosed before age 26 or running in families — to donate blood or saliva samples. Researchers will study the DNA in these samples to look for genetic changes that may explain why cancer developed in the participant or their relatives. This is not clinical genetic testing and results may take years or may never be returned to participants.
Some families have higher rates of cancer because they carry changes in genes that make cancer more likely. By studying DNA from affected families, researchers hope to discover which genetic changes cause inherited cancer risk so that doctors can eventually identify and help at-risk family members earlier.
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You will provide one blood sample (or saliva sample if blood draw is not possible) at St. Jude or a location near you. Researchers will also collect your medical history and family cancer history. If you agree, the study team may contact you once a year to update your health information. Your DNA will be stored and studied to look for genetic changes linked to cancer; if you consent, leftover tumor samples from past treatment may also be studied.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States