Plain-English translation of NCT03105843 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers want to understand why some people develop chronic cough and others develop asthma. This study will have you complete two types of breathing challenge tests—one involving voluntary deep breathing and another involving inhaled mannitol (a salt-like substance)—to see how your airways and cough reflex respond compared to people with different cough conditions.
Chronic cough and cough-variant asthma look similar but may work differently in the body. Scientists don't fully understand what causes these different types of cough, so this research aims to find the underlying differences to eventually help doctors diagnose and treat them better.
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You will visit the research clinic to complete two breathing challenge tests. During these tests, you will breathe deeply on your own for a few minutes, and then inhale a mist containing mannitol while researchers monitor your airways and record any coughing. The tests are designed to be safe and to help researchers understand how your airways respond to these challenges compared to others.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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