Plain-English translation of NCT03105843 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers studied how people's airways reacted to two special breathing tests: one involving voluntary deep breathing and another involving inhaling a powder-like substance. The study compared three groups—people with cough-variant asthma (where cough is the main symptom), people with chronic cough who didn't have asthma, and healthy people with no cough history. The goal was to better understand what causes cough in these different conditions.
Cough-variant asthma and chronic cough can feel similar and are confusing to diagnose, but they may work differently in the body. Researchers wanted to use these special breathing challenge tests to figure out what actually causes cough in each condition, which could help doctors diagnose and treat patients better in the future.
Participants visited the research clinic to undergo two breathing challenge tests. During the first test, they breathed deeply and rapidly on their own. During the second test, they inhaled a special powder that affected moisture and temperature in their airways. Researchers watched how their airways responded and asked about any symptoms they noticed, like cough, to understand how their lungs reacted differently.
AI-generated summary from trial data · Aug 28, 2026 · Not medical advice
Canada