Plain-English translation of NCT03142152 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing the Carillon Mitral Contour System, a small device that doctors place inside your heart to help reduce leakage from your mitral valve — one of your heart's four valves. If your valve is leaking, your heart has to work harder to pump blood, which makes heart failure worse. This study will see if the device, combined with your regular heart failure medications, can help you feel better and live longer.
Many people with heart failure develop a leaky mitral valve because their heart becomes enlarged and weakened. While medications help, they don't always fix the valve problem. This trial exists to see if a less invasive device option can improve symptoms and quality of life for people whose current treatment isn't enough.
You likely qualify if…
You likely don't qualify if…
If you qualify and are randomized, you'll have either the device implant procedure or a similar procedure without the device placement (the control group). After that, you'll return to your cardiologist for follow-up visits at 1, 6, 12, 18, and 24 months, where doctors will check your heart function and symptoms. You'll then have annual visits and heart ultrasounds for three more years, for a total commitment of five years.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
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