Plain-English translation of NCT03190538 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term research study following children ages 1–18 who have been diagnosed with nonalcoholic fatty liver disease (NAFLD)—a condition where fat builds up in the liver without being caused by alcohol. Researchers want to understand how this condition changes over time in children and what specific patterns in the liver tissue mean for their health and future.
Fatty liver disease in children is becoming more common, but doctors don't yet fully understand how it develops or what the long-term risks are. This study exists to fill that gap by tracking children over many years and learning which patterns in liver tissue are serious and which are less concerning.
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You would be part of a long-term follow-up study where researchers track your health over time using medical records and clinical information already collected from your liver biopsy and care. The study involves 400 children total and documents how your condition develops, with the goal of understanding which features of fatty liver disease in children are most important for predicting health outcomes.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
China
Collaborators
Beijing 302 Hospital
Enrollment target
~400 participants
Started
May 2017
Primary completion
May 2027
Age range
1 Year – 18 Years
Last updated on clinicaltrials.gov in July 2026.
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Central contact
George Lau, MD, PhD
Humanity and Health Medical Centre
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