Plain-English translation of NCT03217006 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The ROMA trial is testing whether using multiple arterial grafts during heart bypass surgery leads to better long-term outcomes than using just one arterial graft. In bypass surgery, surgeons use healthy blood vessels (called grafts) to reroute blood around blocked arteries in your heart. This study will compare outcomes for patients who receive one arterial graft versus those who receive two or more arterial grafts.
For decades, doctors have believed that using multiple healthy arteries as grafts during bypass surgery might help patients live longer and avoid future heart problems, but this has never been rigorously tested. This trial exists to definitively answer whether this approach truly improves survival and reduces the need for repeat procedures.
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If you enroll, you will undergo bypass heart surgery and be randomly assigned to receive either one arterial graft (your left internal thoracic artery, with additional vein grafts) or multiple arterial grafts (at least two arteries, and possibly three or four). After surgery, you will be followed by the research team to track your health outcomes, including any future heart events, strokes, or need for repeat procedures. The trial is designed to follow patients for several years to compare long-term results between the two surgical approaches.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
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