Plain-English translation of NCT03217006 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The ROMA trial is testing whether using multiple artery grafts during heart bypass surgery leads to better long-term outcomes than using just one artery graft. Doctors have suspected for years that multiple artery grafts may be better because arteries tend to stay open longer than vein grafts. This large international study will randomly assign heart surgery patients to receive either one artery graft or multiple artery grafts, and then track their health over time to see which approach works better.
While doctors have believed that multiple artery grafts are superior based on smaller studies, there hasn't been a large definitive trial to prove it. This study exists to answer that question with solid evidence so surgeons can be confident they're giving patients the best possible approach.
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If you enroll, you will have heart bypass surgery as planned, but the type of grafts used will be randomly assigned. One group will receive one artery graft plus vein grafts; the other group will receive multiple artery grafts. After surgery, you will have follow-up visits to monitor your heart health and check how well the grafts are working. The study will track outcomes like survival, stroke risk, heart attacks, and the need for repeat procedures over time.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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