Plain-English translation of NCT03225144 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study run by the National Institute of Neurological Disorders and Stroke that aims to better understand diseases like frontotemporal dementia and amyotrophic lateral sclerosis (ALS). Researchers will collect medical information and optional biological samples (like blood, spinal fluid, or skin) from people with these diagnoses or who carry genes linked to them. The goal is to identify patterns, discover shared causes, and find potential treatment targets.
Currently, we don't fully understand why these devastating brain and motor diseases develop or what they have in common at a genetic and cellular level. By studying patients and gene carriers together, researchers hope to uncover new insights that could eventually lead to better treatments and earlier detection.
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You will visit the NIH to undergo clinical tests that measure how your brain and motor functions are working, helping researchers confirm your diagnosis and track disease stage. You can choose to participate in optional research procedures—such as blood draws, skin biopsies, spinal fluid collection, or advanced brain imaging—to provide biological samples for laboratory studies. The study builds a registry of carefully characterized patients and gene carriers to help researchers identify common patterns and differences among these diseases.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States