Plain-English translation of NCT03249519 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether combining standard radiation therapy and chemotherapy with an additional treatment called hyperthermia (controlled heat applied to the cancer area) can improve outcomes for people with advanced cervical cancer. The study will measure whether the added heat treatment helps the radiation and chemotherapy work better at shrinking tumors and improving survival.
Radiation and chemotherapy are already proven treatments for advanced cervical cancer, but researchers believe adding controlled heat to the treatment area might make these therapies more effective. This trial will help determine whether this combination approach leads to better results for patients.
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You would receive a combination of external radiation therapy (50.4 units focused on the cancer), internal brachytherapy (35–40 units delivered directly near the tumor), weekly chemotherapy injections over 6 weeks, and 10 sessions of hyperthermia (where controlled heat is applied to the treatment area). The entire treatment course would occur over several weeks, and you would have regular appointments for each component of your care.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Germany
Sponsor
University of Erlangen-Nürnberg Medical School
Enrollment target
~999 participants
Started
August 2017
Primary completion
December 2094
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in August 2017.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Oliver Ott, MD
University of Erlangen-Nürnberg Medical School
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.