Plain-English translation of NCT03255928 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at how blood clots after you receive a mechanical heart pump (called a VAD, or ventricular assist device). Researchers will use two specialized blood tests — one that measures how active your blood platelets are, and another that measures how well your blood can form clots — to understand what happens to your clotting system after the pump is implanted and over time.
People with heart pumps face real risks: either dangerous blood clots forming inside the device, or dangerous bleeding. Understanding exactly how your blood's clotting ability changes after implantation may help doctors better predict and prevent these serious complications.
You likely qualify if…
You likely don't qualify if…
You will have blood samples taken at several time points: before your pump is implanted (to establish a baseline), shortly after implantation while you're in the hospital, and during follow-up appointments over the course of your support. If you develop any bleeding or clotting complications, additional blood samples will be taken. Your blood samples will be analyzed with the specialized tests, and the results will be compared with your standard clotting blood work and any complications you experience.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
Italy
Collaborators
Università Vita-Salute San Raffaele
Enrollment target
~60 participants
Started
June 2017
Primary completion
December 2026
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Filippo Consolo, PhD
San Raffaele Scientific Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.