Plain-English translation of NCT03286335 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is studying proton radiation therapy, a type of targeted radiation treatment that aims to destroy or shrink benign (non-cancerous) or slow-growing brain tumors in adults. Researchers want to measure how well the treatment controls the tumor, how it affects your quality of life, and what side effects you might experience—both in the short term and up to 5 years after treatment.
While proton radiation therapy has been approved by the FDA for other conditions, it hasn't been officially approved specifically for benign and slow-growing brain tumors. This trial will gather evidence to understand whether this targeted form of radiation is safe and effective for these particular tumors, and how it compares to what we currently know about quality of life outcomes.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will receive proton radiation therapy, typically five days a week on weekdays. Your radiation dose will be determined based on your specific tumor type. The study team will follow your progress for up to 5 years after your treatment ends, checking how well the tumor responds, monitoring your quality of life, and tracking any side effects you experience.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Enrollment target
~100 participants
Started
September 2018
Primary completion
September 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Tarin Grillo
Massachusetts General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.