Plain-English translation of NCT03291652 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand what makes plaque buildup in brain arteries dangerous and more likely to cause a stroke. This study will take detailed pictures of your brain arteries using advanced imaging scans (MRI and specialized X-ray angiography) to study the shape and characteristics of the plaque. By comparing people who have had strokes with those who have plaque but haven't had strokes yet, researchers hope to identify warning signs of dangerous plaque.
Stroke caused by plaque in brain arteries is a serious condition, but doctors don't yet fully understand which plaques are most dangerous. By studying the exact shape and features of plaque in different patients, researchers may be able to predict which patients are at highest risk and develop better ways to prevent future strokes.
You likely qualify if…
You likely don't qualify if…
You will first have an MRI scan of your head and neck arteries to check for plaque buildup. If the scan shows plaque in the right location, you'll have a 30-minute ultrasound test (called TCD) to look for tiny particles traveling in your blood vessels. Then, if you qualify, you'll undergo a specialized angiography procedure where doctors insert a thin tube through an artery in your groin and inject contrast dye to take detailed 3D pictures of your brain arteries. Throughout the study, you'll receive standard stroke-prevention medications and your doctors will monitor your blood work and how you're doing.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Hong Kong
Sponsor
Chinese University of Hong Kong
Enrollment target
~140 participants
Started
February 2010
Primary completion
December 2026
Age range
30 Years – 85 Years
Last updated on clinicaltrials.gov in February 2026.
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Central contact
Thomas Wai Hong LEUNG, FRCP
Chinese University of Hong Kong
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