Plain-English translation of NCT03297606 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
CAPTUR is a Canadian trial testing whether giving patients medications that specifically target genetic mutations found in their individual tumors can be effective. Researchers first identify the genetic changes in your cancer through tumor profiling, then match you with a medication designed to target that specific change. This personalized approach aims to find treatments that work better for your particular cancer.
Advanced cancers often have specific genetic mutations that can be targeted with drugs, but patients haven't had a systematic way to find out if they have these mutations and get the matching treatment. This trial exists to see whether this personalized, genetics-based approach to cancer treatment can help patients whose standard treatments haven't worked or aren't available.
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First, your tumor would be sent for genetic testing to identify actionable mutations. If a match is found between your tumor's genetics and one of the trial medications, you would begin taking that medication and attend regular clinic visits to monitor how well it works and check for side effects. The trial is designed to match you with a treatment based on your unique cancer genetics, rather than treating all patients with the same drug.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Canada