Plain-English translation of NCT03297775 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Rheumatoid Arthritis research guide →Researchers want to better understand lung disease in people with rheumatoid arthritis—especially early signs that show up on imaging before you have symptoms. By following patients over several years with breathing tests, chest scans, and blood work, they hope to identify which people are most likely to develop lung problems and what factors predict worsening disease.
Some people with rheumatoid arthritis develop scarring in their lungs, but doctors don't yet know who will get it or how to predict it. This study aims to find early warning signs and genetic or blood markers that could help doctors catch and treat lung disease before it becomes serious.
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You'll visit the study site once a year for a clinical check-in that includes questions about your health, medications, and quality of life. Every 3 to 5 years, you'll also have more detailed testing: lung function tests (breathing tests), a chest scan (HRCT), and blood draws to look at genetic markers and other biomarkers. The study will continue until it closes, allowing researchers to follow how your lungs change over time.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States
Enrollment target
~750 participants
Started
June 2017
Primary completion
June 2027
Age range
45 Years – 90 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Haylie A Lengel
University of Colorado, Denver
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.