Plain-English translation of NCT03331302 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This research study is testing a newer way to take pictures of your lungs called hyperpolarized xenon-129 MRI, and comparing it to the standard lung imaging test (xenon-133 scintigraphy) that doctors currently use. The researchers want to see if the newer MRI scan can detect small breathing problems in your lungs that the standard test might miss. Both tests are safe and use special gases to help visualize how well your lungs are working.
Current lung imaging tests don't always catch small areas where air isn't flowing properly in COPD patients. This study is exploring whether the newer MRI imaging technique might be better at spotting these problem areas, which could help doctors diagnose and treat COPD more effectively in the future.
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You would undergo two lung imaging tests: first the standard xenon-133 scintigraphy (nuclear medicine scan), then the newer hyperpolarized xenon-129 MRI scan. Each test involves breathing in a special gas while the machine takes pictures of your lungs—each scan takes only about 10 seconds to hold still. The visits are designed to directly compare how well each imaging technique can see how your lungs are working.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
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