Plain-English translation of NCT03354429 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial tested whether , a blood clot-preventing medication, combined with aspirin could better protect people from having another stroke compared to aspirin alone. Researchers studied over 11,000 patients worldwide who had recently experienced a minor stroke or transient ischemic attack (TIA)—sometimes called a 'warning stroke'—to see if the combination treatment would reduce their risk of future stroke and death.
After a minor stroke or TIA, patients remain at high risk for another, more serious stroke. This trial was designed to determine whether adding this medication to the standard aspirin treatment could provide better protection for these vulnerable patients.
Participants were randomly assigned to receive either the study medication combined with aspirin or a placebo pill combined with aspirin. They took their assigned treatment by mouth over a period of time while researchers monitored them for any new stroke events or side effects through follow-up visits and assessments.
AI-generated summary from trial data · Sep 21, 2026 · Not medical advice
Argentina